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Eotaxin

Cat no: E3351-04B

Eotaxin

Chemokines play a key role in inflammation. The CC chemokine eotaxin is a potent and specific eosinophil chemoattractant that is expressed by a variety of cell types in certain inflammatory conditions (1,2). Some G-protein coupled chemokine receptors are also utilized as virus coreceptors for fusion and infection of cells. The eotaxin receptor CCR3 is required for HIV-1 entry into target cells such as microglia and eotaxin inhibits the infection of HIV-1 (3,4).\n\nThis polyclonal antibody can be used for detection of eotaxin by Western blot at 0.5 to 1ug/ml. The recombinant protein can be used as positive control and monomer and homodimer are detected at approximate 9 and 18kD.

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SPECIFICATIONS

Catalog Number

E3351-04B

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, 0.02% sodium azide.

P Type

Pab

Purity

Supplied as purified IgG

Isotype

IgG

References

1. Kitaura M, Nakajima T, Imai T, et al., (1996) J Biol Chem 271:7725-30. 2. Ponath PD, Qin S, Ringler DJ, et al., (1996) J Clin Invest 97:604-12. 3. He J, Chen Y, Farzan M, et al. (1997) Nature 385(6617):645-9. 4. Choe H, Farzan M, Sun Y, et al., (1996) Cell 85:1135-48.

Additional Info

Recognizes human Eotaxin

Read more on Supplier website

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info
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