EP300 (7D8A) Antibody

Cat no: 252813

Supplier: ABBIOTEC

0 reviews | Write a Review Pencil

Description
Additional Information

EP300 (E1A binding protein p300) is an adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It is a histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. p300 has also been identified as a co-activator of HIF1A (hypo, Xenopus/Amphibian,ia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypo, Xenopus/Amphibian,ia-induced genes such as VEGF. Defects in this protein cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

Catalogue number:	252813
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	Q7Z6C1
Antigen:	Purified recombinant fragment of EP300 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	7D8A6
Additional info:	EP300 protein; p300; KAT3B