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EphA1 (Ephrin A1 receptor, Ephrin type-A receptor 1)

Cat no: E3355-01B

EphA1 (Ephrin A1 receptor, Ephrin type-A receptor 1)

EPH receptor A1 (EphA1), with 976aa protein (~107kD), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date and their ligands, the ephrins,can be subdivided into two major subclasses, ephrin-A and ephrin-B. Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior, particularly in the nervous system. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis.\n\nApplications: \nSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry (Frozen and paraffin): 1:200-1:1000\nELISA: 1:10,000\nWestern Blot: 1:200-1:1000\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

E3355-01B

Size

100ug

Applications

ELISA, IHC, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid, 0.03% sodium azide.

P Type

Mab

Purity

Purified

Isotype

IgG1

References

1. Duffy, S.L., et al., (2006) Tam Gene Expr Patterns. Feb 6. 2. Pasquale, E.B. (2005) Nat Rev Mol Cell Biol. Jun; 6(6):462-75.

Additional Info

Recognizes human Ephrin A1 receptor.

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