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Ephrin B1, Recombinant, Human, aa28-237, His-tag (EFNB1, Ephrin B, EphB, EFNB1-A, EPH-related Receptor Tyrosine Kinase Ligand 2, ELK Ligand, ELK-L, EPLG2, LERK2, LERK-2, XlERK)

Cat no: E3371-01U

Ephrin B1, Recombinant, Human, aa28-237, His-tag (EFNB1, Ephrin B, EphB, EFNB1-A, EPH-related Receptor Tyrosine Kinase Ligand 2, ELK Ligand, ELK-L, EPLG2, LERK2, LERK-2, XlERK)

EFNB1, belongs to the Eph family. Ephrins, which act as ligands for Eph receptors, are cell-surface proteins that fall into two categories, ephrin-A and ephrin-B, based on their structure and function. EFNB1 proteins are transmembrane and have conserved cytoplasmic tyrosine residues that are phosphorylated upon interaction with an EphB receptor. Also, EFNB1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration.\n\nSource:\nRecombinant corresponding to aa28-237 from human EFNB1, fused to His-tag at N-terminal expressed in E.coli.\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MLAKNLEPVS WSSLNPKFLS GKGLVIYPKI GDKLDIICPR AEAGRPYEYY KLYLVRPEQA AACSTVLDPN VLVTCNRPEQ EIRFTIKFQE FSPNYMGLEF KKHHDYYITS TSNGSLEGLE NREGGVCRTR TMKIIMKVGQ DPNAVTPEQL TTSRPSKEAD \nNTVKMATQAP GSRGSLGDSD GKHETVNQEE KSGPGASGGS SGDPDGFFNS K\n\nMolecular Weight:\n~25.3kD\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

E3371-01U

Size

100ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.4M urea, 5% glycerol.

Purity

~95% (SDS-PAGE)

References

1. Nagashima K., et al. (2002) Mol Biol Cell. 13:4231-4242. 2. Kalo M S., et al. (1996) J Biol Chem. 276:38940-38948.

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Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

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Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

More info
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