Home  >  Products  >  Epidermal Growth Factor-Like Module-Containing Mucin-Like Receptor 3 (EGF-like Module-containing Mucin-like Hormone Receptor-like 3, EGF-like Module Receptor 3, EMR3, UNQ683/PRO1562)

Epidermal Growth Factor-Like Module-Containing Mucin-Like Receptor 3 (EGF-like Module-containing Mucin-like Hormone Receptor-like 3, EGF-like Module Receptor 3, EMR3, UNQ683/PRO1562)

Cat no: E3375-79G


Supplier: United States Biological
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EMR3 is an Orphan-B GPCR with an unknown ligand. Two variants are produced by alternative splicing. One form encodes a 652-amino acid GPCR consisting of two EGF-like domains and a mucin stalk, while the other is a truncated soluble form containing only two EGF-like domains. EMR3 and EMR2 share a high degree of sequence identity in the transmembrane domains. EMR3 has been reported to be expressed in neutrophils, monocytes, and macrophages. ESTs have been isolated from liver/spleen and mixed libraries. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 21-42ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human Spleen, Lymphocytes Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: E3375-79G
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.7, 0.01% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: Egf-like Module Containing, Mucin-like, Hormone Receptor-like 3
Additional info: Recognizes human EMR3.

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