A polyphenol flavonoid that displays antitumor and antioxidant properties. Inhibits telomerase and DNA methyltransferase (DNMT) and blocks the activation of EGF receptors and HER-2 receptors. Also potently and specifically inhibits chymotrypsin-like activity of the proteasome in vitro (IC50= 86-194nM) and in vivo (IC50=1-10uM).
Solubility:
DMSO or EtOH
Molecular Weight:
~458.37