
Supplier:
United States BiologicalCat no: E3414-22
Epithelial Membrane Antigen (EMA, CA15-3, Polymorphic Epithelial Mucin, PEM, Sialomucin or Episialin, MUC-1)
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SPECIFICATIONS
Catalog Number
E3414-22
Size
1ml
Applications
IHC, WB
Hosts
Mouse
Reactivities
Hum
Form
Supplied as a liquid in PBS, 1% BSA, 0.1% sodium azide.
P Type
Mab
Purity
Ascites
Isotype
IgG1
References
1. Hageman et al. In: Application of monoclonal antibodies in tumour pathology. D. Ruiter, G J Fleuren and S O Warnaar, Martinus Nijhoff pp. 167-190 (1987).
Additional Info
Reactive with Epithelial Sialomucin, a mucous glycoprotein located mainly in the glycocalyx of most glandular epithelial cells and in carcinoma cells. Directed against a 400kD glycoprotein, corresponding to MAM-6. Occasionally, a very weak crossreactivity with sarcomas and brain tumors is observed. It does not react with normal colon or rectal epithelium and colorectal adenomas, whereas colorectal carcinomas stain positive. Does not crossreact with leukemias. Reactive with human. Recommended for Mamma carcinoma.
SUPPLIER INFO
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