Home  >  Products  >  Epsin-1, (EH domain-containing region of Eps15)
Epsin-1, (EH domain-containing region of Eps15)

Epsin-1, (EH domain-containing region of Eps15)

Cat no: E3439-45J

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Epsin-1 is a cytosolic adaptor protein and interacting partner for the EH domain-containing region of Eps15. It is involved in the regulation of clathrin-mediated endocytosis via its direct interactions with clathrin, the clathrin adaptor AP-2, and Eps15 (1-3). Epsin-1 is a cargo-specific adaptor for influenza virus entry through the clathrin-mediated pathway. In addition to being a clathrin-interacting protiein, Epsin-1 is also an ubiquitin-, and phospholipid-interacting protein (4). It also may function in a signaling pathway connecting the endocytic machinery to the regulation of nuclear function (1). Applications: Suitable for use in Immunocytochemistry, Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:500-2000 Immunocytochemistry: 1:100-250 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Manufactured incorporating RabMAb(R) technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Catalogue number: E3439-45J
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunocytochemistry, Western Blot
Size: 100ul
Form: Supplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
P type: Mab
Isotype: IgG
Purity: Supernatant
References: 1. Hyman J, et al. J Cell Biol. 149(3):537-46, 2000. 2. Timsit YE, et al. Biochem Biophys Res Commun. 328(2):550-9, 2005. 3. Rosenthal JA, et al. J Biol Chem. 274(48):33959-65, 1999. 4. Chen C, et al. PNAS 105(33):11790-11795, 2008 .
Additional info: Recognizes human Epsin-1.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave