ER-alpha (N-term) Antibody

Cat no: 251251

Supplier: ABBIOTEC

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Description
Additional Information

The estrogen receptor (ER-alpha) is a nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene e, Xenopus/Amphibian,pression and affect cellular proliferation and differentiation in target tissues. ER-alpha can activate the transcriptional activity of TFF1. ER-alpha binds DNA as a homodimer, and can form a heterodimer with ESR2. ER-alpha interacts with FO, Xenopus/Amphibian,C2,Mouse,AP1S, SLC30A9, UBE1C and the coactivators NCOA3, NCOA5, NCOA6, and NCOA7. Genetic variations in ER-alpha are correlated with bone mineral density (BMD). Low BMD is a risk factor for osteoporotic fracture.

Catalogue number:	251251
Reactivities:	Human, Mouse, Chicken/Bird, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P03372
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ER-alpha.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Estrogen receptor; ER; Estradiol receptor; ER-alpha; Nuclear receptor subfamily 3 group A member 1; ESR1; ESR; NR3A1