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ER-beta (N-term) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251152

ER-beta (N-term) Antibody

Estrogen receptor beta (ER-beta) is a nuclear hormone receptor. ER-beta binds estrogens with an affinity similar to that of ESR1, and activates e, Xenopus/Amphibian,pression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. ER-beta binds DNA as a homodimer, and can form a heterodimer with ESR1. ER-beta interacts with NCOA3, NCOA5 and NCOA6 coactivators, leading to a strong increase of transcription of target genes.

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SPECIFICATIONS

Catalog Number

251152

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ER-beta.

Isotype

Rabbit Ig

Accession

Q92731

Additional Info

Estrogen receptor; ER; Estrogen receptor-beta; Estrogen receptor beta; Nuclear receptor subfamily 3 group A member 2; ESR2; ESTRB

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