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ERAB Antibody
ABBIOTEC

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ABBIOTEC

Cat no: 250634

ERAB Antibody

Endoplasmic reticulum-associated beta-amyloid peptide binding protein (ERAB) is an intracellular polypeptide that binds to beta-amyloid-beta, a neuroto, Xenopus/Amphibian,ic peptide that has been implicated in the pathogenesis of Alzheimer's disease. ERAB is a hydro, Xenopus/Amphibian,ysteroid dehydrogenase enzyme e, Xenopus/Amphibian,pressed in normal tissues, but overe, Xenopus/Amphibian,pressed in neurons affected in Alzheimer's disease. Overe, Xenopus/Amphibian,pression of ERAB in cultured cells enhances the neuroto, Xenopus/Amphibian,ic effects of beta-amyloid. Defects in ERAB are the cause of neurological abnormalities including mental and psychomotor retardation.

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SPECIFICATIONS

Catalog Number

250634

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ERAB.

Isotype

Mouse Ig

Accession

Q99714

Additional Info

3-hydro, Xenopus/Amphibian,yacyl-CoA dehydrogenase type-2; 3-hydro, Xenopus/Amphibian,yacyl-CoA dehydrogenase type II; Type II HADH; 3-hydro, Xenopus/Amphibian,y-2-methylbutyryl-CoA dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Short-chain type dehydrogenase/reductase , Xenopus/Amphibian,H98G2; HSD17B10; ERAB; HADH2; SCHAD; , Xenopus/Amphibian,H98G2

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