ErbB3, CT (Receptor Tyrosine-protein Kinase erbB-3, Proto-oncogene-like Protein c-ErbB-3, Tyrosine Kinase-type Cell Surface Receptor HER3, HER3)

Cat no: E3451-35G1

Supplier: United States Biological

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c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 0.1-0.3ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	E3451-35G1
Reactivities:	Human
Hosts:	Goat
Applications:	ELISA, Immunohistochemistry, Western Blot
Size:	50ug
Form:	Supplied as a liquid in TBS, 0.5% BSA, 0.02% sodium azide.
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
Additional info:	Recognizes human ERBB3. Species sequence homology: Canine, mouse and rat.

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ErbB3, CT (Receptor Tyrosine-protein Kinase erbB-3, Proto-oncogene-like Protein c-ErbB-3, Tyrosine Kinase-type Cell Surface Receptor HER3, HER3)

Cat no: E3451-35G1

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