Erk1/2 (3F8) Antibody

Cat no: 252974

Supplier: ABBIOTEC

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Description
Additional Information

ERK1 and ERK2 (E, Xenopus/Amphibian,tracellular signal-regulated kinase 1 and 2) are members of the MAP kinase signal transduction pathway. The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases,Porcine44 and p42 encoded by ERK1 and ERK2 respectively. Both kinases are regulated by dual specific phosphorylation on tyrosine and threonine in response to insulin and NGF. ERK1 and ERK2 are involved in both the initiation and regulation of meiosis,Mouse,itosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1.

Catalogue number:	252974
Reactivities:	Human, Mouse
Applications:	Flow Cytometry
Size:	0.1 ml
Accession:	P27361,Porcine28482
Antigen:	Purified recombinant fragment of human MAPK1 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG2b
Clonality:	3F8
Additional info:	ERK-1; Mitogen-activated protein kinase 3; E, Xenopus/Amphibian,tracellular signal-regulated kinase 1; Insulin-stimulated MAP2 kinase; MAP kinase 1; MAPK1; p44-ERK1; ERT2; p44-MAPK; Microtubule-associated protein 2 kinase; MAPK3; ERK1; PRKM3; and for ERK-2; Mitogen-activated protein kinase 1; E, Xenopus/Amphibian,tracellular signal-regulated kinase 2; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK2; p42-MAPK; ERT1; MAPK1; ERK2; PRKM1; PRKM2