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Erythropoietin Receptor (EPOr)

Erythropoietin Receptor (EPOr)

Cat no: E3455-23

Supplier: United States Biological
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The human erythropoietin receptor (EpoR) is located on stem and mature cells of the hematopoietic system. When activated by its native ligand, erythropoietin (Epo), EpoR mediates proliferation and maturation of the erythroid precursor cells leading to expansion of red cell populations. Human recombinant Epo is currently used for treatment of patients undergoing erythrocyte depletion due to dialysis for kidney failure. Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation and Immunocytochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add glycerol (40-50%) and aliquot. Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: E3455-23
Reactivities: Human
Hosts: Sheep
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Size: 250ug
Form: Supplied as a liquid in PBS, pH 7.2.
P type: Pab
Purity: Purified by Protein G affinity chromatography.
Alternative names: MGC138358
References: 1. Nakatsuji T. Haema 2005; 8(3):450-457. 2. Fairchild Benyo D, (1999) Biol Reprod. Apr;60(4):861-70. 3. Harris KW, J Biol Chem. (1992) Jul 25;267(21):15205-9.
Additional info: Antibody titers and specificity were analyzed by ELISA assay using control samples by varying concentration of GST-EpoR and control anti-GST antibody. Species Crossreactivity: This product is reactive against human. It has not been tested in other species.

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