Home  >  Products  >  Estrogen Receptor, alpha (ERa)
Estrogen Receptor, alpha (ERa)

Estrogen Receptor, alpha (ERa)

Cat no: E3565-09Z

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Estrogen Receptor alpha is a 65kD protein and a member of the steroid family of nuclear receptors. Estrogen Receptor alpha is a ligand-activated transcription factor that, when bound to estrogen, induces a conformational change that allows dimerization and binding to estrogen response element sequences. When bound to DNA, Estrogen Receptor alpha can positively or negatively regulate gene transcription. Cellular Localization: Nuclear Positive Control: MCF-7 whole cell lysate. Applications: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: E3565-09Z
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Immunoprecipitation, Western Blot
Size: 50ug
Form: 0.02% Sodium Azide; PBS. pH 7.4
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Blobel GA & Orkin SH (1996) Mol Cell Biol 16:1687-94. 2. Kraus WL et al. (1995) Proc Natl Acad Sci USA 92:12314-8. 3. Gaub MP et al. (1990) Cell 63:1267-76.
Additional info: Species Crossreactivity: Crossreacts with Human. Expected to crossreact with canine (91% identity with immunogen), Goat (91% identity with immunogen), porcine (91% identity with immunogen), Sheep (91% identity with immunogen) due to sequence homology.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave