Home  >  Products  >  Estrogen Receptor, beta 2 (ER beta, ER-beta, ERb, ESR beta, ESRB, ESTRB, Estrogen Receptor 2, ESR2, MYEB, Nuclear Receptor Subfamily 3 Group A Member 1, NR3A2)
Estrogen Receptor, beta 2 (ER beta, ER-beta, ERb, ESR beta, ESRB, ESTRB, Estrogen Receptor 2, ESR2, MYEB, Nuclear Receptor Subfamily 3 Group A Member 1, NR3A2)

Estrogen Receptor, beta 2 (ER beta, ER-beta, ERb, ESR beta, ESRB, ESTRB, Estrogen Receptor 2, ESR2, MYEB, Nuclear Receptor Subfamily 3 Group A Member 1, NR3A2)

Cat no: E3565-15N

Supplier: United States Biological
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Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 1:10-1:50 Requires antigen retrieval using heat treatment prior to staining of paraffin sections. Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: E3565-15N
Reactivities: Human
Hosts: Mouse
Applications: Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in PBS, 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Supernatant
References: 1. Saunders P. et al. (2002) ERbeta1 and the ERbeta2 splice variant (ERbetacx/beta2) are expressed in distinct cell populations in the adult human testis. J. Clin. Endocrinol. Metab. 87: 2706-2715, 2. Critchley T. et al. (2002) Wild-type estrogen receptor (ERbeta1) and the splice variant (ERbetacx/beta2) are both expressed within the human endometrium throughout the normal menstrual cycle. J. Clin. Endocrinol. Metab. 87: 5265-5273, 3. Gaskell T. et al. (2003) Differential expression of two estrogen receptor beta isoforms in the human fetal testis during the second trimester of pregnancy. J. Clin. Endocrinol. Metab. 88: 424-432, 4. Scobie G. et al. (2002) Human oestrogen receptors: differential expression of ER alpha and beta and the identification of ER beta variants. Steroids 67: 985-995, 5. Wong, N. A. C. S. et al. (2005) ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates. J. Pathol. 207: 53-60.
Additional info: Recognizes human estrogen receptor beta 2 isoform. No cross-reactivity is seen with estrogen receptor beta 1 isoform.

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