Home  >  Products  >  Estrogen Receptor, beta (ERb, ER-beta, Nuclear Receptor Subfamily 3 Group A Member 2, ESR2, ESTRB, NR3A2)
Estrogen Receptor, beta (ERb, ER-beta, Nuclear Receptor Subfamily 3 Group A Member 2, ESR2, ESTRB, NR3A2)

Estrogen Receptor, beta (ERb, ER-beta, Nuclear Receptor Subfamily 3 Group A Member 2, ESR2, ESTRB, NR3A2)

Cat no: E3558-40D

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Estrogen regulates various physiological functions upon binding to its specific receptors. Estrogen receptors (ERs) are members of the nuclear receptor superfamily of ligand-dependent transcription factors that regulate the expression of target gene. ERa and ERb, which are encoded by different genes, have similar overall structure with at least three functional domains in common: the ligand-binding domain located at the C-terminal half of the proteins, the DNA-binding domain located centrally, and the N-terminus. Both ERa and ERb are co- expressed in the same cells such as brain, pituitary, and mammary gland. The co-expression of the two isoforms is a key determinant in the cellular responses to estrogen. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-2ug/ml Optimal dilutions to be determined by the researcher. Positive Control: NIH/3T3 cell lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: E3558-40D
Reactivities: Human, Mouse, Rat, Non-Human Primate
Hosts: Rabbit
Applications: Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Matsuda, K.I. et al. Molecular Endocrinology 16 (10): 2215-2230 (2003). 2. Jefferson, W.N. et al. Biology of Reproduction 67: 1285-1296 (2002). 3. Kawata, M. Neurosci. Res. 24:1-46 (1995).
Additional info: Recognizes human Estrogen Receptor beta. Species Crossreactivity: mouse, monkey and rat.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave