Home  >  Products  >  Estrogen-Related Receptor, gamma (ERR gamma, ERRg, ESRRG, DKFZP781L1617, Estrogen Receptor Related Protein 3, ERR3, FLJ16023, KIAA0832, Nuclear Receptor Subfamily 3 Group B Member 3, NR3B3)
Estrogen-Related Receptor, gamma (ERR gamma, ERRg, ESRRG, DKFZP781L1617, Estrogen Receptor Related Protein 3, ERR3, FLJ16023, KIAA0832, Nuclear Receptor Subfamily 3 Group B Member 3, NR3B3)

Estrogen-Related Receptor, gamma (ERR gamma, ERRg, ESRRG, DKFZP781L1617, Estrogen Receptor Related Protein 3, ERR3, FLJ16023, KIAA0832, Nuclear Receptor Subfamily 3 Group B Member 3, NR3B3)

Cat no: E3565-22B

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Estrogen-related receptor gamma (ERR gamma) is a member of the nuclear hormone receptor superfamily. The fasting-induced coactivator protein PGC-1alpha has been shown to activate the ERR gamma, and together these proteins have a major role in the regulation of ERR alpha gene expression and energy homeostasis. ERR gamma and alpha are co-expressed in high energy demanding tissues such as skeletal muscle heart and kidney, and have been suggested to function in their differentiation. ERR gamma has also been shown to be over-expressed in breast tumors, and has been suggested to be a potential biomarker for favourable clinical course and hormonal sensitivity. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Paraffin): Requires antigen retrieval using heat treatment for 20 minutes prior to staining of paraffin sections. 0.01M sodium citrate buffer, pH 6.0 is recommended. Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies I1904-39: IgG, X-Adsorbed (HRP) Pab Gt xRb I1904-40A: IgG, H&L, X-Adsorbed (HRP) Pab Gt xRb I1904-46Q: IgG, H&L (HRP) Pab Gt xRb Positive Control: Kidney Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: E3565-22B
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in PBS, 0.01% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Zhang, Z. and Teng, C.T. (2007) Interplay between estrogen-related receptor alpha (ERRalpha) and gamma (ERRgamma) on the regulation of ERRalpha gene expression. Mol. Cell. Endocrinol. 264: 128-141.
Additional info: Recognizes human Estrogen-Related Receptor, gamma. Species Crossreactivity: mouse, rat.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave