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ETEA (FAS-associated Factor 2, Protein ETEA, FAF2, UBX Domain-containing Protein 3B, UBX Domain-containing Protein 8, KIAA0887, UBXD8, UBXN3B)

ETEA (FAS-associated Factor 2, Protein ETEA, FAF2, UBX Domain-containing Protein 3B, UBX Domain-containing Protein 8, KIAA0887, UBXD8, UBXN3B)

Cat no: E8445-40A

Supplier: United States Biological
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FAF2 (FAS-associated factor 2), otherwise known as UBXD8 (UBX domain-containing protein 8), is a protein highly expressed in the brain, which is implicated in the transport of damaged ER membrane proteins to the cytoplasm, for degradation by the 20S proteasome. Expression of FAF2 is up-regulated in T-cells and eosinophils from patients with atopic dermatitis (AD), where it may act as a regulator of resistance to apoptosis. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: >1:4000 Western Blot: 1-3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human testes, MOLT-4, or Jurkat Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: E8445-40A
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Imai Y, Nakada A, Hashida R, Sugita Y, Tanaka T, Tsujimoto G, Matsumoto K, Akasawa A, Saito H, Oshida T. Cloning and characterization of the highly expressed ETEA gene from blood cells of atopic dermatitis patients.Biochem Biophys Res Commun. 2002 Oct 11;297(5):1282-90. PMID: 12372427.
Additional info: Recognizes human ETEA. Species sequence homology: mouse and rat.

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