ETEA (FAS-associated Factor 2, Protein ETEA, FAF2, UBX Domain-containing Protein 3B, UBX Domain-containing Protein 8, KIAA0887, UBXD8, UBXN3B)

FAF2 (FAS-associated factor 2), otherwise known as UBXD8 (UBX domain-containing protein 8), is a protein highly expressed in the brain, which is implicated in the transport of damaged ER membrane proteins to the cytoplasm, for degradation by the 20S proteasome. Expression of FAF2 is up-regulated in T-cells and eosinophils from patients with atopic dermatitis (AD), where it may act as a regulator of resistance to apoptosis.\n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nELISA: >1:4000\nWestern Blot: 1-3ug/ml\nOptimal dilutions to be determined by the researcher.\n\nPositive Control:\nHuman testes, MOLT-4, or Jurkat\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

E8445-40A

Size

100ug

Applications

ELISA, WB

Hosts

Goat

Reactivities

Hum

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1. Imai Y, Nakada A, Hashida R, Sugita Y, Tanaka T, Tsujimoto G, Matsumoto K, Akasawa A, Saito H, Oshida T. Cloning and characterization of the highly expressed ETEA gene from blood cells of atopic dermatitis patients.Biochem Biophys Res Commun. 2002 Oct 11;297(5):1282-90. PMID: 12372427.

Additional Info

Recognizes human ETEA. Species sequence homology: mouse and rat.