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ETV4 (1A2G) Antibody

ETV4 (1A2G) Antibody

Cat no: 252793

Supplier: ABBIOTEC
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ETV4 (Ets variant gene 4), also known as PEA3. Several members of the Ets gene family are known to encode sequence specific DNA binding proteins. These include mouse PU.1,Mouse,ouse and human Ets-1, Drosophila E74, chicken and human Ets-2 and rat GABP-?. Each of these proteins recognizes similar motifs in DNA that share a centrally located 5'-GGAA-3' element. For instance,PorcineEA3 binds the motif 5'-AGGAAG-3' (the PEA-3 motif), but does not bind to the sequence 5'-AGGAAC-3', recognized by PU.1, although PU.1 binds equally well to both sequences. It appears that all of the Ets proteins recognize the same central core sequence but that each protein interacts with unique sequences that flank this core. PEA3 is e, Xenopus/Amphibian,pressed at readily detectable levels in cells of epithelial and fibroblastic origin but is not e, Xenopus/Amphibian,pressed in hematopoietic cells. This is in contrast to other members of the Ets gene family, such as Ets-1, Ets-2 and Fli-1, each of which is e, Xenopus/Amphibian,pressed primarily in cells of hematopoietic origin.
Catalogue number: 252793
Reactivities: Human
Applications: Western Blot
Size: 0.1 ml
Accession: P43268
Antigen: Purified recombinant fragment of human ETV4 (aa50-109) e, Xenopus/Amphibian,pressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: 1A2G3
Additional info: ETS translocation variant 4; Adenovirus E1A enhancer-binding protein; E1A-F; Polyomavirus enhancer activator 3 homolog; Protein PEA3; E1AF; PEA3; ETV4
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