F12 (Coagulation Factor XII, Hageman Factor, HAF)

Cat no: F0019-45L

Supplier: United States Biological

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Additional Information

Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	F0019-45L
Reactivities:	Human
Hosts:	Sheep
Applications:	ELISA, Immunohistochemistry, Western Blot
Size:	500ug
Form:	Supplied as a liquid in 0.05M sodium phosphate, 0.1M sodium chloride, 1mM EDTA, pH 6.6.
P type:	Pab
Isotype:	IgG
Purity:	Purified by Protein G affinity chromatography.
Additional info:	Recognizes human F12.

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F12 (Coagulation Factor XII, Hageman Factor, HAF)

Cat no: F0019-45L

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