FABP3 (Fatty Acid-binding Protein, Heart, Heart-type Fatty Acid-binding Protein, H-FABP, Fatty Acid-binding Protein 3, Muscle Fatty Acid-binding Protein, M-FABP, Mammary-derived Growth Inhibitor, MDGI, FABP11)

Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins (14-15kD) that bind long chain fatty acids, their CoA derivatives, bilirubin, organic anions and other small hydrophobic molecules. Their primary role is the regulation of fatty acid uptake and intracellular transport. (1) To date, nine different fatty acid binding proteins have been identified and named by tissue of first discovery or numerically by gene. (1-9) Fatty acid binding proteins are abundantly present in numerous cell types and due to their small size, can rapidly leak from cells after trauma. As such, the measurement of elevated levels of fatty acid binding proteins in serum can be used as a diagnostic marker to monitor the extent of tissue damage.\n\nApplications:\nSuitable for use in ELISA, Western Blot, Dot Blot, Immunohistochemistry, Immunoassays, development of rapid tests and other antibody recognition assays. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

F0019-76L1

Size

100ug

Applications

ELISA, IHC, WB

Hosts

Sheep

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

P Type

Mab

Purity

Purified by Protein A affinity chromatography.

References

1. Chmurzynska A. J. Appl. Genet. 2006, 47(1): 39-48. 2. Entrez Gene: FABP1 fatty acid binding protein1, liver. 3. Lieberman JM et al. Surgery. 1997, 121(3): 335-342. 4. Lescuyer P et al. Mol Diagn. 2005, 9(1): 1-7. 5. Zimmerman A W & Veerkamp JH. Cell Mol Life Sci 2005, 59(7): 1096-1116. 6. Siegenthaler G et al.. Biochem Biophys Res Commun. 2003, 190(2): 482

Additional Info

Recognizes FABP3.