Factor B Antibody

Cat no: 250119

Supplier: ABBIOTEC

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Description
Additional Information

The complement factor B is part of the alternate pathway of the complement system. Factor B is cleaved by factor D into two fragments, Ba and BBovine, the latter being a serine protease that binds to complement component 3b (C3b) to generate the C3 or C5 convertase. Factor B is involved in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. Among the 15 variants of factor B gene, the variants His-9 and Gln-32 are associated with a reduced risk of age-related macular degeneration (ARMD). This antibody recognizes human complement factor B in indirect and sandwich ELISA.

Catalogue number:	250119
Reactivities:	Human
Size:	0.1 mg
Accession:	P00751, NP_001701
Antigen:	Purified human complement factor B protein
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	mouse IgG2b
Clonality:	KT21
Additional info:	Complement factor B; C3/C5 convertase; Properdin factor B; Glycine-rich beta glycoprotein; GBG; PBF2; Ba fragment; Bb fragment; CFB; BF; BFD