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MtoZ Biolabs

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Factor I Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250120

Factor I Antibody

The complement factor I is responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. These protein cleavages inactivate complement components C3Bovine, iC3b and C4b. Factor I consists of a heterodimer of a light and heavy chains linked by disulfide bonds. Factor I deficiencies (CFI) result in increasing risks for pyrogenic infections, such as hemolytic uraemic syndrome (HUS), an acute renal failure in childhood due to E. coli infection. This antibody recognizes human complement factor I in ELISA.

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SPECIFICATIONS

Catalog Number

250120

Size

0.1 mg

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

Purified human complement factor I protein

Isotype

mouse IgG2b

Accession

P05156, NP_000195

Clonality

KT22

Additional Info

Complement factor I; C3B/C4B inactivator; Factor I heavy chain; Factor I light chain; CFI; IF

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