Factor I Antibody

Cat no: 250120

Supplier: ABBIOTEC

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Description
Additional Information

The complement factor I is responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. These protein cleavages inactivate complement components C3Bovine, iC3b and C4b. Factor I consists of a heterodimer of a light and heavy chains linked by disulfide bonds. Factor I deficiencies (CFI) result in increasing risks for pyrogenic infections, such as hemolytic uraemic syndrome (HUS), an acute renal failure in childhood due to E. coli infection. This antibody recognizes human complement factor I in ELISA.

Catalogue number:	250120
Reactivities:	Human
Size:	0.1 mg
Accession:	P05156, NP_000195
Antigen:	Purified human complement factor I protein
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	mouse IgG2b
Clonality:	KT22
Additional info:	Complement factor I; C3B/C4B inactivator; Factor I heavy chain; Factor I light chain; CFI; IF