Home  >  Products  >  Factor VII (Coagulation Factor VII, F7, Eptacog alfa, Proconvertin, Serum Prothrombin Conversion Accelerator, SPCA)
Factor VII (Coagulation Factor VII, F7, Eptacog alfa, Proconvertin, Serum Prothrombin Conversion Accelerator, SPCA)

Factor VII (Coagulation Factor VII, F7, Eptacog alfa, Proconvertin, Serum Prothrombin Conversion Accelerator, SPCA)

Cat no: F0015-19A

Supplier: United States Biological
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Factor VII is a serine protease found circulating in the blood. It initiates the extrinsic pathway of blood coagulation in conjunction with tissue factor. Tissue factor is found on the outside of blood vessels. When the vessels is damaged, tissue factor is exposed to the blood and circulating Factor VII. Once bound to tissue factor, Factor VII is activated by different proteases and converts Factor IX to IXa. Factor VII deficiency is a rare hereditary haemorrhagic disease. Symptoms range from mild to severe. Applications: Suitable for use in ELISA, Western Blot and RIA. Other applications have not been tested. Recommended Dilutions: ELISA: 1:20-1:200 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F0015-19A
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 200ug
Form: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
Alternative names: Coagulation Factor VII (Serum Prothrombin Conversion Accelerator), EC=3.4.21.21
References: 1. Takase, T. et al. (1988) Monoclonal antibodies to human factor VII: a one step immunoradiometric assay for VII:Ag. J. Clin. Pathol. 41: 337
Additional info: Recognizes human Factor VII. Binds to a conformational epitope and will not bind to reduced Factor VII.

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