Factor XIIIa (Coagulation Factor XIII A Chain, Coagulation Factor XIIIa, Protein-glutamine gamma-glutamyltransferase A Chain, Transglutaminase A Chain, F13A)

Supplier:

United States Biological

Cat no: F0019-50Y

Factor XIIIa (Coagulation Factor XIII A Chain, Coagulation Factor XIIIa, Protein-glutamine gamma-glutamyltransferase A Chain, Transglutaminase A Chain, F13A)

Factor XIII in both reduced and non-reduced forms. It does not react with human Factor XIII B-chain or human Factor XII. Factor XIII is a b-globulin found in plasma and is composed of two subunits. Factor XIII-A is the catalytic subunit and is a dimer with the molecular weight of 160kD. Factor XIII is present in plasma as a a2b2 heterodimer with the molecular weight of 320kD. Whereas in platelets, Factor XII is found to exists as a a2 unit. Factor XIIIa is a dermal dendrocyte marker and shows variable reaction with these types of tumors. It can be used for histiocytic phenotyping, with the reported ability to identify capillary hemangiomas and tumors of the central nervous system.\n\nApplications:\nSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1-2ug/ml for 2hr, RT\nImmunohistochemistry(Formalin fixed paraffin embedded): 1:50 for 30min at RT \nOptimal dilutions to be determined by the researcher.\n\nPositive Control:\nRecombinant human Factor XIII A subunit, capillary hemangioma, dermatofibroma, placenta\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

F0019-50Y

Size

50ug

Applications

IHC, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG1,k

Additional Info

Recognizes human Factor XIIIa.

Read more on Supplier website

SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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