Home  >  Products  >  FANCJ (FANCJ protein, BACH 1, BACH1, BRIP1, BRIP 1, BRAC 1 Associated C Terminal Helicase 1, BRCA 1 Interacting Protein 1)
FANCJ (FANCJ protein, BACH 1, BACH1, BRIP1, BRIP 1, BRAC 1 Associated C Terminal Helicase 1, BRCA 1 Interacting Protein 1)

FANCJ (FANCJ protein, BACH 1, BACH1, BRIP1, BRIP 1, BRAC 1 Associated C Terminal Helicase 1, BRCA 1 Interacting Protein 1)

Cat no: F0019-58W9C

Supplier: United States Biological
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BRIP1 (also called BACH1 /FANCJ) is a helicase that interacts with the BRCT domain of BRCA1 and has a role in BRCA1-dependent DNA repair and checkpoint. BRIP1 has recently been found to be defective in Fanconi anemia complementation group J. BRIP1/FANCJ has a function in the Fanconi anemia pathway that is independent of BRCA1 and downstream of FANCD2 activation. (1-4) Positive Control: HeLa whole cell extract and Raji, 293, MCF7 and SKOV3 whole cell extracts. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: F0019-58W9C
Reactivities: Human
Hosts: Rabbit
Applications: Immunoprecipitation, Western Blot
Size: 100ul
Form: As reported
P type: Pab
Purity: Whole antisera
Alternative names: FANCJ protein, BACH 1, BACH1, BRIP1, BRIP 1, BRAC 1 Associated C Terminal Helicase 1, BRCA 1 Interacting Protein 1
References: 1. Cantor, S., et al. BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cell 105: 149-160, 2001. (Western Blot, Immunoprecipitation, human)
Additional info: This antibody is specific for BACH1/Brip1/FANCJ. Species Crossreactivity: recognizes human Brip1/FANCJ

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