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Fanconi anemia G (Fanconi anemia Group G Protein, Protein FACG, DNA-repair protein XRCC9)

Fanconi anemia G (Fanconi anemia Group G Protein, Protein FACG, DNA-repair protein XRCC9)

Cat no: F0019-58W8

Supplier: United States Biological
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FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified. Cellular Localization: The major form is nuclear. The minor form is cytoplasmic. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: F0019-58W8
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ul
Form: As reported
P type: Pab
Purity: Whole antisera
Alternative names: Fanconi anemia Group G Protein, Protein FACG, DNA-repair protein XRCC9
References: 1. Park, S-J., et al. Oxidative stress/damage induces multimerization & intederaction of fanconi anmeia proteins. J. Biol. Chem. 279: 30053-30059 (2004)
Additional info: Species Crossreactivity: This antibody reacts with the human protein.

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