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Fas (ALPS1A, Apo-1 Antigen, Apoptosis-mediating Surface Antigen FAS, APT1, CD95, FAS1, FASLG Receptor, FASTM, Tumor Necrosis Factor Receptor Superfamily Member 6, TNFRSF6)

Fas (ALPS1A, Apo-1 Antigen, Apoptosis-mediating Surface Antigen FAS, APT1, CD95, FAS1, FASLG Receptor, FASTM, Tumor Necrosis Factor Receptor Superfamily Member 6, TNFRSF6)

Cat no: F0019-61G

Supplier: United States Biological
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Human CD95 (APO-1/FAS) is a type I cell surface glycoprotein that is strongly upregulated on activated T cells, B cells, NK cells and thymocytes. CD95 plays an important role in programmed cell death or apoptosis. Apoptosis appears to be a mechanism for regulating the immune response. Applications: Suitable for use in ELISA and Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F0019-61G
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Flow Cytometry
Size: 100ug
Form: Supplied as a liquid in 50mM sodium phosphate, pH 7.5, 100mM potassium chloride, 50mM sodium chloride. No preservative added.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein A affinity chromatography.
Alternative names: Fas (TNF Receptor Superfamily, Member 6)
References: 1. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford (1995) p. 1142-1148, 2. S. Nagata & P. Golstein, (1995) Science 267: 1449-1456, 3. S. Nagata & T. Suda, (1995) Immunol Today 16: 39-43, 4. D.H. Lynch, F. Ramsdell & M.R. Alderson, (1995) Immunol Today 16: 569-574, 5. H Wajant, (2003) Essays Biochem 39:53-71.
Additional info: Recognizes cell surface expressed human CD95. Does not induce apoptosis.

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