Fascin (Singed-like Protein, 55kD Actin-bundling Protein, p55, SNL, HSN, FAN1, FSCN1)

Cat no: F0019-96F

Supplier: United States Biological

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Human fascin is a highly conserved actin-bundling protein. Fascin, encoded by the human homolog for sn (hsn) gene. Localized in microspikes and stress fibers of cultured cells, it is hypothesize to be involved in the formation of microfilament bundles. Fascin expression is predominantly located in dendritic cells, while negative in regions of lymphoid, myeloid, and plasma cells. However, Reed Sternberg cells in Hodgkin's lymphoma are positive for fascin staining. Epstein-Barr virus may induce expression of fascin in B cells. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 1:50 for 10min at RT Staining of formalin-fixed tissues requires boiling tissues sections in 10mM citrate buffer, pH 6.0, for 10min followed by cooling at RT for 20min Optimal dilutions to be determined by the researcher. Positive Control: Hodgkin

Catalogue number:	F0019-96F
Reactivities:	Human, Rat
Hosts:	Mouse
Applications:	Immunohistochemistry
Size:	50ug
Form:	Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
P type:	Mab
Isotype:	IgG1
Purity:	Purified
Additional info:	Recognizes Fascin. Species Crossreactivity: human and rat.

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Fascin (Singed-like Protein, 55kD Actin-bundling Protein, p55, SNL, HSN, FAN1, FSCN1)

Cat no: F0019-96F

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