FasL Antibody

Cat no: 250646

Supplier: ABBIOTEC

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Description
Additional Information

Fas ligand (FasL or CD95L) is a cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptoic signal into cells. FasL is involved in cytoto, Xenopus/Amphibian,ic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis has a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T cells or both. Defects in FasL are the cause of autoimmune lymphoproliferative syndrome 1B (ALPS1B), a childhood syndrome involving hemolytic anemia and thrombocytopenia.

Catalogue number:	250646
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P48023
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human FasL.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	FasL; Tumor necrosis factor ligand superfamily member 6; Fas antigen ligand; Fas ligand; CD95L protein; Apoptosis antigen ligand; APTL; CD178; FASLG; APT1LG1; FASL; TNFSF6