Fatty Acid Binding Protein 7, Brain (FABP7, B-FABP, Brain Lipid Binding Protein, BLBP, DKFZp547J2313, FABPB, MRG)

Supplier:

United States Biological

Cat no: F0019-90B

Fatty Acid Binding Protein 7, Brain (FABP7, B-FABP, Brain Lipid Binding Protein, BLBP, DKFZp547J2313, FABPB, MRG)

The FABP family is a group of small highly conserved cytoplasmic proteins that bind long chain fatty acids and other hydrophobic ligands. Research suggests that FABPs are involved in fatty acid uptake, transport and metabolism. \n\nFABP7 is expressed in the brain and other neurological tissues. FABP7 is an important component in the establishment of the radial glial fiber system in the developing brain, a system that is required for the migration of immature neurones to establish cortical layers. \n\nStudies have also demonstrated that FABP7 is frequently expressed in melanomas.\n\nApplications: \nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 0.5-1ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

F0019-90B

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, 0.02% sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1. Goto, Y., et al. (2006) A new melanoma antigen fatty acid-binding protein 7, involved in proliferation and invasion, is a potential target for immunotherapy and molecular target therapy. Cancer Res.; 66:4443-9. 2. Chmurzynska, A. (2006) The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism. J. Appl. Genet.; 47:39-48. 3. Arai, Y., et al. (2005) Role of FABP7, a downstream gene of pax6, in the maintenance of neuroepithelial cells during early embryonic development of the rat cortex. J. Neurosci.; 25:9752-61. 4. Shimizu, F., et al. (1997) Isolation and expression of a cDNA for human brain fatty acid-binding protein (B-FABP). Biochim. Biophys. Acta; 1354:24-28.

Additional Info

Recognizes human FABP7.

Alternative Names

Fatty Acid Binding Protein 7 (Brain), Brain Fatty Acid Binding Protein

Read more on Supplier website

SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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