Home  >  Products  >  Fatty Acid Binding Protein 7, Brain (FABP7, B-FABP, Brain Lipid Binding Protein, BLBP, DKFZp547J2313, FABPB, MRG)

Fatty Acid Binding Protein 7, Brain (FABP7, B-FABP, Brain Lipid Binding Protein, BLBP, DKFZp547J2313, FABPB, MRG)

Cat no: F0019-90B


Supplier: United States Biological
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The FABP family is a group of small highly conserved cytoplasmic proteins that bind long chain fatty acids and other hydrophobic ligands. Research suggests that FABPs are involved in fatty acid uptake, transport and metabolism. FABP7 is expressed in the brain and other neurological tissues. FABP7 is an important component in the establishment of the radial glial fiber system in the developing brain, a system that is required for the migration of immature neurones to establish cortical layers. Studies have also demonstrated that FABP7 is frequently expressed in melanomas. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: F0019-90B
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: Fatty Acid Binding Protein 7 (Brain), Brain Fatty Acid Binding Protein
References: 1. Goto, Y., et al. (2006) A new melanoma antigen fatty acid-binding protein 7, involved in proliferation and invasion, is a potential target for immunotherapy and molecular target therapy. Cancer Res.; 66:4443-9. 2. Chmurzynska, A. (2006) The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism. J. Appl. Genet.; 47:39-48. 3. Arai, Y., et al. (2005) Role of FABP7, a downstream gene of pax6, in the maintenance of neuroepithelial cells during early embryonic development of the rat cortex. J. Neurosci.; 25:9752-61. 4. Shimizu, F., et al. (1997) Isolation and expression of a cDNA for human brain fatty acid-binding protein (B-FABP). Biochim. Biophys. Acta; 1354:24-28.
Additional info: Recognizes human FABP7.

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