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FBXL21 Polyclonal Antibody

Cat no: CAC07687

FBXL21 Polyclonal Antibody

FBXL21 Polyclonal Antibody

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SPECIFICATIONS

Price

323.00 USD

Catalog Number

CAC07687

Size

100 micro g

Applications

IF, IHC, WB

Hosts

Rabbit

Conjugates

Unconj

Purity

Protein G purified, >95%

Target

FBXL21

Clonality

Polyclonal

Storage Temp

Aliquot and store at -20 degrees C. Minimize freezing and thawing.

Research Area

For research use only. Not for diagnostic procedures.

Shipping Temp

Blue ice

Additional Info

Substrate-recognition component of the SCF(FBXL21) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL21) complex mainly acts in the cytosol and mediates ubiquitination of CRY proteins (CRY1 and CRY2), leading to CRY proteins stabilization. The SCF(FBXL21) complex counteracts the activity of the SCF(FBXL3) complex and protects CRY proteins from degradation. Involved in the hypothalamic suprachiasmatic nucleus (SCN) clock regulating temporal organization of the daily activities (By similarity).

Alternative Names

F-box/LRR-repeat protein 21,F-box and leucine-rich repeat protein 21,F-box and leucine-rich repeat protein 3B,F-box/LRR-repeat protein 3B,FBXL21,FBL21,FBL3,FBXL3B,FBXL3P

SUPPLIER INFO

Biomatik Corporation

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