Home  >  Products  >  FCER2 (5B5) Antibody
FCER2 (5B5) Antibody

FCER2 (5B5) Antibody

Cat no: 253097

Supplier: ABBIOTEC
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
FCE2 (Human leukocyte differentiation antigen CD23) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor. It is e, Xenopus/Amphibian,pressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells), and can also be found on the surface of T cells,Mouse,acrophages,Porcinelatelets and EBV transformed B lymphoblasts. E, Xenopus/Amphibian,pression of CD23 has been detected in neoplastic cells from cases of B cell chronic Lymphocytic leukemia. CD23 is e, Xenopus/Amphibian,pressed by B cells in the follicular mantle but not by proliferating germinal centre cells. CD23 is also e, Xenopus/Amphibian,pressed by eosinophils. CD23 is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface e, Xenopus/Amphibian,pression appears to be integral with the comple, Xenopus/Amphibian, IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a
Catalogue number: 253097
Reactivities: Human
Applications: Immunofluorescence
Size: 0.1 ml
Accession: P06734
Antigen: Purified recombinant fragment of human FCER2 e, Xenopus/Amphibian,pressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: 5B5
Additional info: Low affinity immunoglobulin epsilon Fc receptor; BLAST-2;C-type lectin domain family 4 member J; Fc-epsilon-RII; Immunoglobulin E-binding factor; Lymphocyte IgE receptor; CD23
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave