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SPECIFICATIONS
Price
323.00 USD
Catalog Number
CAC07640
Size
100 micro g
Applications
IF, IHC, WB
Hosts
Rabbit
Conjugates
Unconj
Purity
Protein G purified, >95%
Target
FCGR2B
Clonality
Polyclonal
Storage Temp
Aliquot and store at -20 degrees C. Minimize freezing and thawing.
Research Area
For research use only. Not for diagnostic procedures.
Shipping Temp
Blue ice
Additional Info
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Alternative Names
Low affinity immunoglobulin gamma Fc region receptor II-bIgG Fc receptor II-b,CDw32,Fc-gamma RII-b,Fc-gamma-RIIb,FcRII-b,CD32,FCGR2B,CD32,FCG2,IGFR2
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