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Fibrin Degradation Product, D-Dimer

Fibrin Degradation Product, D-Dimer

Cat no: F4197-17B

Supplier: United States Biological
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Human D-dimer protein is a blood test performed in the medical laboratory to diagnose thrombosis. Since human D-Dimer(s) introduction, human D-Dimer protein has become an important test performed in patients suspected of thrombotic disorders. While a negative human D-Dimer result practically rules out thrombosis, a positive human D-Dimer result can indicate thrombosis but also has other potential causes. Human D-Dimer(s) main use is to exclude thromboembolic disease where the probability is low. Human D-dimer testing is of clinical use when there is a suspicion of deep venous thrombosis (DVT) or pulmonary embolism (PE). In patients suspected of disseminated intravascular coagulation (DIC), Human D-dimer(s) protein may aid in the diagnosis. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: F4197-17B
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 1mg
Form: Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
P type: Mab
Isotype: IgG2a
Purity: Purified by Protein A affinity chromatography.
Additional info: Recognizes human D-dimer (Fibrin Degradation Product). Recognizes high molecular weight fibrin degradation products. Recognizes D-dimer in Western blot under non-reducing conditions. Interacts with beta-chain of D-dimer in Western blot under reducing conditions. Does not cross-react with fibrinogen and D-monomer.

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