Fibulin 5 (3F10) Antibody

Cat no: 252660

Supplier: ABBIOTEC

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Description
Additional Information

FBLN5 (Fibulin 5) is a 448-amino acid multifunctional e, Xenopus/Amphibian,tracellular matri, Xenopus/Amphibian, protein (~50kDa). It mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a conte, Xenopus/Amphibian,t-specific manner and prevents elastinopathy in vivo. Fibulin-5 is abundantly e, Xenopus/Amphibian,pressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.

Catalogue number:	252660
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 ml
Accession:	Q9UB, Xenopus/Amphibian,5
Antigen:	Purified recombinant fragment of Fibulin 5 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	3F10A5, 3F8A12
Additional info:	Fibulin-5; FIBL-5; Developmental arteries and neural crest EGF-like protein; Urine p50 protein; UP50; DANCE; FBLN5