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FITC anti-human CD107a (LAMP-1)

FITC anti-human CD107a (LAMP-1)

Cat no: 328606

Supplier: BioLegend
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CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane gly­coprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. It is expressed by activated platelets, acti­vated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. This molecule is located on the luminal side of lysosomes and has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases. Upon activation, CD107a is transferred to the cell membrane surface. It plays a role in cell adhesion and regula­tion of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin.
Catalogue number: 328606
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100 tests
Clone: H4A3
Gene: 3916
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microl to 5 microl per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microl staining volume or per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Read more at www.biolegend.com/testsize regarding the test size change.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Antigen: Human adult adherent peripheral blood cells
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: LAMP1, LGP-120
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