FITC anti-mouse CD104

CD104 is a 205 kD type I transmembrane glycoprotein, known as integrin beta4 chain or beta4 integrin, that associates with integrin alpha6 (CD49f) forms alpha6/beta4 (CD49f/CD104) heterodimer. CD104 is expressed on epithelial cells (especially on the proliferative basal layer epithelial cells in skin), endothelial cells, Schwann cells, certain tumor cells and a subset of pre-T cells. CD49f/CD104 is an adhesion receptor for laminins (especially laminin 5) and keratin filaments and is involved in the regulation of hemidesmosome formation and of cell proliferation and activation.

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SPECIFICATIONS

Catalog Number

123605

Size

50 microg

Applications

FC

Hosts

Rat

Reactivities

Mouse

Clone

346-11A

Antigen

Tumor-associated antigen TSP-180 from BALB/c lung carcinoma

Gene Id

192897

Isotype

Rat IgG2a, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

Integrin b4, b4 Integrin, TSP-1180

Regulatory Status

RUO