FITC anti-mouse/human GL7 Antigen (T and B cell Activation Marker)

The GL7 antigen, also known as Ly77, is a 35 kD protein. The GL7 antigen has an epitope containing non-sulfated alpha2-6-sialyl-LacNAc recognized by the GL7 antibody. The GL7 antigen is expressed by pre-B and immature B cells, activated T and B cells, and about 20% of TCR-bright thymocytes. It is up-regulated on mouse splenocytes following activation. It may play a role in regulation or adhesion. GL7 high-expressing B cells show higher antibody production and antigen presenting capacity.

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SPECIFICATIONS

Catalog Number

144603

Size

50 microg

Applications

FC

Hosts

Rat

Reactivities

Hum, Mouse

Clone

GL7

Antigen

LPS activated DBA/J mouse B cells

Isotype

Rat IgM, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

Ly-77, Ly77, T and B cell activation marker, GL-7

Regulatory Status

RUO