FITC anti-mouse I-Ak (Aalphak)

Cat no: 110006

Supplier: BioLegend

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Description
Additional Information

The 11-5.2 antibody reacts with the alpha chain of the I-Ak MHC class II alloantigen. These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2k bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins. The 11-5.2 antibody cross-reacts with cells from mice bearing the H-2r haplotype. Reactivity with other H-2 haplotypes (e.g., b, d, f, p, q, s) has not been observed. The 11-5.2 antibody has been reported to block antigen presentation and induce B cell differentiation.

Catalogue number:	110006
Reactivities:	Mouse
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	500 microg
Clone:	11-5.2
Gene:	14960
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration:	0.5 mg/ml
Antigen:	CKB mouse splenocytes
Isotype:	Mouse (BALB/c) IgG2b, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	A alpha, Aalpha, IA alpha