FITC anti-mouse Siglec H

Cat no: 129603

Supplier: BioLegend

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Description
Additional Information

The Siglec-H is a member of CD33-related Siglec family which mostly expressed in the innate immune system. Siglec-H is reported to be specifically expressed on plasmacytoid dendritic cells. Siglec-H depends on adaptor protein DAP 12 (DNAX-activating protein of 12 kD) for surface expression and signal transduction. Cross-linking with this antibody can selectively inhibit interferon-alpha production by IPCs following TLR9 ligation.

Catalogue number:	129603
Reactivities:	Mouse
Hosts:	Rat
Applications:	Flow Cytometry
Size:	50 microg
Clone:	551
Gene:	233274
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.25 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration:	0.5 mg/ml
Antigen:	Siglec-H-Fc recombinant fusion protein
Isotype:	Rat IgG1
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Siglec-H, Sialic acid-binding immunoglobulin-like lectin