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FITC anti-mouse TCR Vbeta8.1, 8.2

FITC anti-mouse TCR Vbeta8.1, 8.2

Cat no: 118406

Supplier: BioLegend
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The TCR Vbeta 8 family consists of three members, namely Vbeta8.1, 8.2 and 8.3. KJ16-133.18 reacts with Vbeta8.1, 8.2 only, but not Vbeta8.3. Most mouse strains have about 20% Vbeta 8+ T cells in the periphery.However, C57BR, C57L, SJL, SWR (Tcra haplotype) and RIII strains (Tcrc haplotype) do not express Vbeta8 due to a gene deletion at the Vbeta 8 family loci.Other strains expressing endogenous super-antigen, such as Mls-1a have significant reduced number of Vbeta 8.1 cells in the periphery.Exogenous superantigen, such as staphylococcal enterotoxin B, stimulates lymphocytes bearing Vbeta 8 and selectively eliminate those T cells in vivo.
Catalogue number: 118406
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry
Size: 100 microg
Clone: KJ16-133.18
Gene: 21577
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration: 0.5 mg/ml
Antigen: TCR receptor from T cell hybridoma DO-11.10
Isotype: Rat IgG2a, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: T cell receptor Vb8.1, 8.2 chain, TCR Vb8.1, 8.2
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