FITC anti-mouse TCR Vbeta8.3

Cat no: 118603

Supplier: BioLegend

0 reviews | Write a Review Pencil

Description
Additional Information

The Vbeta8.3 TCR is a variant of the TCR beta chain. It is expressed by a subset of peripheral blood T cells and is increased in response to some viral infections and tumors. T cells expressing the alpha/beta T cell receptor use clonally distributed TCRs to recognize cell-bound antigens such as peptide/MHC complexes and viral superantigens. The alpha/beta TCR is an oligomeric TCR complex composed of covalently bound alpha and beta chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3delta, gamma, epsilon, and ? chains. The 8C1 antibody has been used for the identification of T cells expressing Vbeta8.3 by flow cytometry.

Catalogue number:	118603
Reactivities:	Mouse
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	50 microg
Clone:	8C1
Gene:	21577
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration:	0.5 mg/ml
Isotype:	Mouse IgG2a
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	T cell receptor Vb8.3