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FITC anti-mouse TCR Vgamma1.1/Cr4

FITC anti-mouse TCR Vgamma1.1/Cr4

Cat no: 141103

Supplier: BioLegend
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T cell receptor (TCR) is a heterodimer consisting of an alpha and beta chain (TCR alpha/beta) or a gamma and delta chain (TCR gamma/delta). TCR associates with CD3 to form a CD3/TCR complex. The CD3/TCR plays a key role in antigen recognition, signal transduction, and T cell activation. TCR Vgamma1.1 (Garman nomenclature) is also called TCR Vgamma1 (Tonegawa nomenclature). The Vgamma1 gene almost exclusively rearranges to the Jgamma4-Cgamma4 gene. Vgamma1- Jgamma4-Cgamma4 expressing cells constitute a major population of gamma/delta T cells in thymus and peripheral lymphoid organs in adult mice, but they are only composed of a minor population of gamma/delta T cells during fetal and early postnatal life. Vgamma1 T cell development can happen in thymus-dependent and thymus-independent manners. Further studies have shown that the antibody 2.11 recognized epitote is located in Cr4 domain.
Catalogue number: 141103
Reactivities: Mouse
Applications: Flow Cytometry
Size: 25 microg
Clone: 2.11
Gene: 110067
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration: 0.5 mg/ml
Antigen: T3.13.1 T-cell hybridoma cell line
Isotype: Armenian hamster IgG
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: T cell receptor Vgamma 1.1, TCR Vgamma1
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