FITC anti-rat CD25

Cat no: 202103

Supplier: BioLegend

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Description
Additional Information

CD25 is a 55 kD glycoprotein also known as IL-2 receptor alpha chain. It is broadly expressed on activated T and B cells, a subset of thymic and splenic dendritic cells, and intestinal epithelial cells in the rat. IL-2 is a critical cytokine involved in lymphocyte proliferation and clonal expansion. IL-2 signaling requires the high affinity IL-2 receptor composed of IL-2 receptor chains alpha, beta, and gamma. The OX-39 antibody weakly inhibits IL-2 binding to the IL-2 receptor and has been shown to block some IL-2 mediated responses in vitro.

Catalogue number:	202103
Reactivities:	Rat
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	100 microg
Clone:	OX-39
Gene:	16184
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 1.0 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration:	0.5 mg/ml
Antigen:	Rat T cell blasts from mixed lymphocyte reactions
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	IL-2Ra, IL-2 receptor chain a