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Products FK-866 (K 22.175, FK866, APO866, WK175, N-3-(3-pyridinyl)-2E-propenamide)
| Catalogue number: | 044815 |
| Size: | 1mg |
| Purity: | >98% (NMR) |
| Alternative names: | K 22.175, FK866, APO866, WK175, N--3-(3-pyridinyl)-2E-propenamide |
| References: | Product Reference: ?FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis: M. Hasmann & I. Schemainda; Cancer Res. 63, 7436 (2003) ?NAD depletion by FK866 induces autophagy: R.A. Billington, et al.; Autophagy 4, 385 (2008) ?Extension of human cell lifespan by nicotinamide phosphoribosyltransferase: E. van der Veer, et al.; J. Biol. Chem. 282, 10841 (2007) ?Antiangiogenic potency of FK866/K22.175, a new inhibitor of intracellular NAD biosynthesis, in murine renal cell carcinoma: J. Drevs, et al.; Anticancer Res. 23, 4853 (2003) ? |
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