FK506 Binding Protein 2, aa22-142, Recombinant, Human (FKBP2, FKBP-2, 13kD FK506-binding Protein, 13kD FKBP, FKBP13, FKBP-13, Immunophilin FKBP13, Peptidyl-prolyl Cis-trans Isomerase FKBP2, PPIase FKBP2, Rotamase)

Supplier:

United States Biological

Cat no: F4150-13H

FK506 Binding Protein 2, aa22-142, Recombinant, Human (FKBP2, FKBP-2, 13kD FK506-binding Protein, 13kD FKBP, FKBP13, FKBP-13, Immunophilin FKBP13, Peptidyl-prolyl Cis-trans Isomerase FKBP2, PPIase FKBP2, Rotamase)

FKBP2 is peptidyl proline isomerase enzyme and a member of the immunophilin protein family. This protein is predominantly expressed in thymus and T cells and plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. FKBP2 is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Recombinant FKBP2 protein was expressed in E. coli.\n\nSource: \nRecombinant corresponding to aa22-142 of human FKBP2 expressed in E. coli.\n\nAA Sequence:\nMATGAEGKRK LQIGVKKRVD HCPIKSRKGD VLHMHYTGKL EDGTEFDSSL PQNQPFVFSL GTGQVIKGWD QGLLGMCEGE KRKLVIPSEL GYGERGAPPK IPGGATLVFE VELLKIERRT EL\n\nApplications: \nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

F4150-13H

Size

50ug

Applications

WB

Form

Supplied as a liquid in 20mM Tris buffer, pH 8.0, 1mM DTT, 10% glycerol.

Purity

~ 90% (SDS-PAGE). Purified by using conventional chromatography techniques.

References

1. Walensky LD., et al. (1998) J Cell Biol. 141(1):143-53. 2. Padilla PI., et al. (2003) Proc Natl Acad Sci U S A. 100(5):2322-7.

Alternative Names

13kD FKBP, EC=5.2.1.8, FK506-binding Protein 2

Read more on Supplier website

SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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