Home  >  Products  >  Flagellin (FliC)
Flagellin (FliC)

Flagellin (FliC)

Cat no: 044817

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system. Biological Activity: Activation of TLR5 in human epithelial cell assays based on NF-kappaB luciferase fusions, on expression of IL-8 (CXCL8), CCL20, inducible nitric oxide synthase, beta-defensin 2 and matrilysin (MMP-7). Maturation of dendritic cells in in vitro and in vivo assays. Adjuvant activity on foreign antigens delivered by subcutaneous and intranasal routes in mice. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Stable for at least 6 months after receipt when stored at -20 degrees C.
Catalogue number: 044817
Size: 100ug
Form: Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
Purity: >90% (SDS-PAGE)
Alternative names: FliC
References: Product Reference: ?Deletion of flagellin's hypervariable region abrogates antibody-mediated neutralization and systemic activation of TLR5-dependent immunity: C. Nempont, et al.; J. Immunol. 181, 2036 (2008) ?
Additional info: Binds to human and mouse TLR5 (Toll-like receptor 5).

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave