FMR1 (4G9) Antibody

Cat no: 252868

Supplier: ABBIOTEC

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Description
Additional Information

FMR1 (Fragile , Xenopus/Amphibian, mental retardation protein 1) is an RNA-binding protein. FMR1 associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an e, Xenopus/Amphibian,pansion to 55-230 repeats is the cause of fragile , Xenopus/Amphibian, syndrome. E, Xenopus/Amphibian,pansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.

Catalogue number:	252868
Reactivities:	Human
Applications:	Immunofluorescence, Immunohistochemistry
Size:	0.1 ml
Accession:	Q06787
Antigen:	Purified recombinant fragment of human FMR1 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	4G9
Additional info:	POF; FMRP; POF1; FRA, Xenopus/Amphibian,A; Fragile , Xenopus/Amphibian, mental retardation protein 1; FMRP; Protein FMR-1; FMR1